Key Moments
The Red Devils' poor recent struggles persisted at Elland Road, but head coach Ruben Amorim had Matheus Cunha to thank for his side avoiding even more disappointment against their old rivals.
Dominic Calvert-Lewin headed a first-period attempt against the post for the in-form hosts before Brenden Aaronson applied a cool finish with a low, 62nd-minute shot.
With the goal, the United boss was under intense scrutiny after his side had been held by struggling Wolverhampton Wanderers at Old Trafford earlier in the week.
Nevertheless, against a team who had two days less to prepare, Cunha restored parity three minutes later when he latched onto a pass from substitute the Dutchman and guided a finish underneath rushing home goalkeeper Lucas Perri.
It was only the Brazilian's fourth goal since his big-money summer move and came at a time when the manager is without several key attacking players due to a mix of fitness issues and national team commitments.
Not that you would expect Leeds to care about that given their own lack of preparation time.
The Swiss attacker forced a full length save out of Manchester United goalkeeper Senne Lammens with a spectacular overhead kick, and visiting heads were in hands when Benjamin Sesko, who is finding it hard to make an impact, turned Zirkzee's cut-back wide from six yards out.
Cunha, who had a goal ruled out for offside much earlier in the match, also fired against a post in the dying moments.
The draw extends the home side's unbeaten run to seven matches, their longest such streak since 2001, and takes them eight points clear of the relegation zone.
For the Manchester United though, it was yet another opportunity to move into fourth spot, albeit only for a short time, squandered.
With the AFCON reaching its latter stages, Amorim could be understood for hoping the participating nations make a pretty quick exit.
Current injuries to skipper Bruno Fernandes and England international Mason Mount only heightened the impact the absence of other attackers is having on Amorim's options.
It's not that the missing pair are the solution to all of United's problems. After all, they were part of the side that experienced poor results earlier in the season.
But without them, the boss has limited attacking options.
He clearly does not trust youngster Shea Lacey or the seasoned Zirkzee, even though the Dutch forward delivered the through ball for Cunha's equaliser almost instantly after his introduction as a replacement.
That leaves Cunha, who has now scored a small tally in five games, and others playing out of their preferred positions, alongside Sesko.
On this showing, the expensive frontman looks no better than previous struggling signings, lacking in confidence and conviction in front of goal.
His failure to turn home the cross means it is now nine games without a goal for the new signing.
After thrilling victories in their last few home games, the arrival of their biggest rivals to Elland Road was a bit drab affair.
True, there were instances of typical atmosphere, but the intimidating edge was not as pronounced as in other encounters.
Leeds' fans were more concerned about their side's inability to get sustained possession in dangerous areas for any prolonged period.
The striker's header that clipped the post was an isolated moment of threat in a tight first half.
It still felt as though the hosts were finding it tough when a defensive error opened the door for the opener.
For a short moment, Leeds' delirious fans thought they were about to secure a coveted win against their old foes.
However, there is a wider context for the manager and the club to deal with.
When they suffered a poor run of form earlier in the campaign, many thought about the manager's position.
Instead, he is now masterminding clear improvement.
The job is not completed yet but gradually, Leeds are getting closer to achieving their top-flight status.
The Yorkshire club have a top-flight trip to St James' Park in midweek, followed by the start of their FA Cup campaign next weekend. The Red Devils face a league trip to Turf Moor before also beginning their FA Cup journey with a home tie.
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Stephanie Gordon
Stephanie Gordon
Stephanie Gordon
Stephanie Gordon
Stephanie Gordon